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Scientific References

Palombo P, Fabrizi G, Ruocco V, Ruocco E, Flühr J, Roberts R, Sousa-Martins D, and Morganti P. New Evidence for Efficacy of Lutein/Zeaxanthin in Skin Health. Beyond Beauty Paris 2006 Conference Abstract, 2006.

2006

     

Rerksuppaphol, S; Rerksuppaphol, L. Effect of fruit and vegetable intake on skin carotenoid detected by non-invasive Raman spectroscopy. J Med Assoc Thai. 2006; 89(8):1206-12

2006

     

Darvin, M; Zastrow, L; Sterry, W; Lademann, J. Effect of supplemented and topically applied antioxidant substances on human tissue. Skin Pharmacol Physiol. 2006; 19(5):238-47

2006

     

Wisniewska A, Widomska J, and Subczynski WK. Carotenoid — membrane interactions in liposomes: effect of dipolar, monopolar, and nonpolar carotenoids. Acta Biochimica Polonica, Paper in Press, No. 1328. 2006 Sep 11 (epub).

2006

     

Santocono M, Zurria M, Berrettini M, Fedeli D, Falcioni G. Influence of astaxanthin, zeaxanthin and lutein on DNA damage and repair in UVA-irradiated cells. J Photochem Photobiol B. 2006 Sep 7; [Epub ahead of print]

2006

     

Rabe J., Mamelak A, et al. Photoaging: Mechanisms and repair. J. Am Acad Dermatology 2006;55:1-19

2006

     

Heinrich U, Tronnier H, Stahl W, Bejot M, Maurette JM. Antioxidant Supplements Improve Parameters Related to Skin Structure in Humans. Skin Pharmacol Physiol. 2006 May 4;19(4):224-231 [Epub ahead of print]

2006

     

Pintea A, Diehl H, Momeu C, Aberle L, Socaciu C. Incorporation of carotenoid esters into liposomes. Biophysical Chemistry 2005;118:7–14.

2005

     

Lutein and Zeaxanthin - Monograph. Altern Med Rev. 2005 Jun;10(2):128-135.

2005

     

Stahl W, Sies H. Bioactivity and protective effects of natural carotenoids. Biochim Biophys Acta. 2005 May 30;1740(2):101-7.

2005

     

McNaughton SA, Marks GC, Gaffney P, Williams G, Green AC. Antioxidants and basal cell carcinoma of the skin: A nested case-control study. Cancer Causes Control. 2005 Jun;16(5):609-18.

2005

     

Millen AE, Tucker MA, Hartge P, Halpern A, Elder DE, Guerry D 4th, Holly EA, Sagebiel RW, Potischman N. Diet and melanoma in a case-control study. Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):1042-51.

2004

     

Lee EH, Faulhaber D, Hanson KM, Ding W, Peters S, Kodali S, Granstein RD. Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression. J Invest Dermatol. 2004 Feb;122(2):510-7.

2004

     

Dorgan JF, Boakye NA, Fears TR, Schleicher RL, Helsel W, Anderson C, Robinson J, Guin JD, Lessin S, Ratnasinghe LD, Tangrea JA. Serum carotenoids and alpha-tocopherol and risk of nonmelanoma skin cancer. Cancer Epidemiol Biomarkers Prev. 2004 Aug;13(8):1276-82.

2004

     

Morganti P, Fabrizi G, Bruno C. Protective effects of oral antioxidants on skin and eye function. Skinmed. 2004 Nov-Dec;3(6):310-6.

2004

     

Chaparro RS, Carr E, Barron JL. Hypercarotenaemia or hypercarotenoidaemia. Ann Clin Biochem. 2003 May;40(Pt 3):280-2.

2003

     

Gonzalez S, Astner S, An W, Goukassian D, Pathak MA. Dietary lutein/zeaxanthin decreases ultraviolet B-induced epidermal hyperproliferation and acute inflammation in hairless mice. J Invest Dermatol. 2003 Aug;121(2):399-405.

2003

     

Mukhtar H. Eat plenty of green leafy vegetables for photoprotection: emerging evidence. J Invest Dermatol. 2003 Aug:121(2):vii.

 

2003

     

Sies H, Stahl W. Non-nutritive bioactive constituents of plants: lycopene, lutein and zeaxanthin. Int J Vitam Nutr Res. 2003 Mar;73(2):95-100.

 

2003

     

Heinrich U, Gartner C, Wiebusch M, Eichler O, Sies H, Tronnier H, Stahl W. Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. J Nutr. 2003 Jan;133(1):98-101.

 

2003

     

Fung TT, Spiegelman D, Egan KM, Giovannucci E, Hunter DJ, Willett WC. Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin. Int J Cancer. 2003 Jan 1;103(1):110-5.

 

2003

     

Morganti P, Bruno C, Guarneri F, Cardillo P, Del Ciotto P, Valenzano F. Role of topical and nutritional supplement to modify the oxidative stress. Int J Cosmetic Sci. 2002 24:331-339.

 

2002

     

Stahl W, Sies H. Carotenoids and protection against solar UV radiation. Skin Pharmacol Appl Skin Physiol. 2002 Sep-Oct;15(5):291-6. Review.

 

2002

     

Eichler O, Sies H, Stahl W. Divergent optimum levels of lycopene, beta-carotene and lutein protecting against UVB irradiation in human fibroblasts. Photochem Photobiol. 2002 May;75(5):503-6.

 

2002

     

Bruch-Gerharz D, Stahl W, Gerharz CD, Megahed M, Wingerath T, Sies H, Ruzicka T. Accumulation of the xanthophylls lutein in skin amyloid deposits of systemic amyloidosis (AL type). J Invest Dermatol. 2001 Jan;116(1):196-197.

 

2001

     

Nagao T, Warnakulasuriya S, Ikeda N, Fukano H, Yamamoto S, Yano M, Miyazaki H, Ito Y. Serum antioxidant micronutrient levels in oral lichen planus. J Oral Pathol Med. 2001 May;30(5):264-7.

 

2001

     

Lee J, Jiang S, Levine N, Watson R. Carotenoid supplementation reduces erythema in human skin after simulated solar radiation exposure. Proc Soc Exp Biolog Med. 2000 223:170-174.

 

2000

     

Hata TR, Scholz TA, Ermakov IV, McClane RW, Khackik F, Gellermann W, Pershing LK. Non-invasive raman spectroscopic detection of carotenoids in human skin. J Invest Dermatol. 2000 Sep:115(3):441-448.

 

2000

     

Stahl W, Heinrich U, Jungmann H, Sies, H, Tronnier H. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans. Am J Clin Nutr. 2000 71:795-798.

 

2000

     

Stahl W, Heinrich U, Jungmann H, von Laar J, Schietzel M, Sies H, Tronnier H. Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting Betatene. J Nutr. 1998 128:903-907.

 

1998

     

Wingerath T, Sies H, Stahl W. Xanthophyll esters in human skin. Arch Biochem Biophy. 1998 Jul;355(2):271-274.

 

1998

     

Taylor EJ, Evans FJ. Anti-psoriatic action of lutein demonstrated by inhibition of rat photodermatitis. J Pharm Pharmacol. 1998 50(Supp):78.

 

1998

     

O'Connor I, O'Brian N. Modulation of UVA light-induced oxidative stress by B-carotene, lutein and astaxanthin in cultured fibroblasts. J Dermat Sci. 1998 16:226-230.

 

1998

     

Rocchi E, Stella AM, Cassanelli M, Borghi A, Nardella N, Seium Y, Casalgrandi G. Liposoluble vitamins and naturally occurring carotenoids in porphyria cutanea tarda. Eur J Clin Invest. 1995 Jul;25(7):510-4.

 

1995

     

Peng YM, Peng YS, Lin Y. A nonsaponification method for the determination of carotenoids, retinoids, and tocopherols in solid human tissues. Cancer Epidemiol Biomarkers Prev. 1993 Mar-Apr;2(2):139-44.

 

1993

     

Peng YM, Peng YS, Lin Y, Moon T, Baier M. Micronutrient concentrations in paired skin and plasma of patients with actinic keratoses: effect of prolonged retinol supplementation. Cancer Epidemiol Biomarkers Prev. 1993 Mar-Apr;2(2):145-50.

 

1993

     

Nierenberg DW, Nann SL. A method for determining concentrations of retinol, tocopherol, and five carotenoids in human plasma and tissue samples. Am J Clin Nutr. 1992 Aug;56(2):417-26.

 

1992

 

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